In What Way Bacterial Cell Recognizes Its Individual DNA

Source:

Weizmann Institute of Science, ScienceDaily 

Rendering of bacteria. Bacteria have an immune system

 to fight off invasive viruses called phages, scientists say

What is the undertaking of CSIR ?

Council of Scientific and Industrial Research

Council of Scientific and Industrial Research (CSIR) established in 1942, is an autonomous body and India's largest research and development (R&D) organisation, with 37 laboratories and 39 field stations or extension centres spread across the nation, with a collective staff of over 17,000 see for more CSIR Wiki

fingerprint does not contain your genetic code

...THE POWER of genetic information has shaped virtually every aspect of medicine. On one hand, we have learned about diseases and treatments that are now defined by patients’ genomes. Certain genes can predict colorectal cancer with near certainty and, in women, the BRCA mutations, famously discussed by Angelina Jolie, can denote a greater than 80 percent risk of developing breast cancer. We can screen newborns for dozens of genetic diseases and immediately know which diets to avoid giving them or which medications to begin early. Physicians are using genetic markers to better tailor therapies to individual patients. We are certainly entering a new era. 

How dengue virus enters cells found

Scientists have unveiled the mechanism behind how dengue enters cells of our immune system, a finding that could help develop vaccine for the deadly virus. 

Dengue fever, an infectious tropical disease caused by a mosquito-borne virus, afflicts millions of people each year, causing fever, headache, muscle and joint pains and a characteristic skin rash, researchers said. In some people the disease progresses to a severe, often fatal, form known as dengue hemorrhagic fever.

Liquid Crystal Soft Matter Improves Biosensing

Plop living, swimming bacteria into a novel water-based, nontoxic liquid crystal and a new physics takes over. The dynamic interaction of the bacteria with the liquid crystal creates a novel form of soft matter: living liquid crystal.

New spider species discovered in Kerala

Aranmula: Three new species of spiders have been discovered near the proposed airport site at Aranmula in Pathanamthitta district, Kerala.

The research team, led by AV Sudhikumar, an arachnologist with the Zoology Department of Christ College, Irinjalakuda, has discovered three new and eight rare species of spiders on the proposed airport site.

Young Researcher Award 2014

Lady Tata Memorial Trust

Founded 1932

Bombay House, Homi Mody Street

         Mumbai 400 001

Applications are invited for the ‘Young Researcher Award – 2014’

Mitochondria Isolated Their Waste

Nov-29-2013.....In order to protect themselves from harmful substances, cells need to keep the mitochondria -- the boiler room, so to speak -- shipshape. Up to now, it was unclear whether this housekeeping work involves sorting out defective proteins when they digest mitochondria. Dr. Jörn Dengjel from the Center for Biological Systems Analysis (ZBSA), Freiburg Institute for Advanced Studies (FRIAS), and the Cluster of Excellence BIOSS Centre for Biological Signaling Studies of the University of Freiburg has now discovered in collaboration with researchers from the Hebrew University in Jerusalem, Israel, that the proteins are sorted out during the constant fusion and fission of mitochondria. The team published their findings in the journal Nature Communications. 

Regional Centre for Biotech RCB Young Investigator Awards 2012

Regional Centre for Biotechnology

An Institution of Education, Training and Research

(Established by the Dept of Biotechnology, Govt of India under the auspices of UNESCO)

Adv. No. 8/2012

Nobel Prize in Physiology or Medicine 2012

Nobel Prize in Physiology or Medicine 2012 for Stem Cell Work

CCMP Open Day Entry Free

CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY,

HYDERABAD

The First mammalian 'cell phone'

Researchers from ETH Zurich designed a “cell phone” made of biological components. A “therapeutical call” halts the pathological formation of new blood vessels. Credit: Andrea Lingk / ETH Zurich

Adult Stem Cells

Anxieties about Stem Cells

Stem cells

Despite the enormous therapeutic potential for stem cells to treat a vast array of serious diseases there are still concerns about potentially dangerous results. Scientists are excited about the possibilities of saving lives and reducing morbidity from disease but at the same time, there are fears regarding unexpected results and effects from stem cell usage. With recent technologies having triggered a major increase in stem cell treatments, the concept of stem cell therapies is no longer such a foreign one.

Study shows clathrin protein moonlights, playing key role in cell division

A protein called "clathrin," which is found in every human cell and plays a critical role in transporting materials within them, also plays a key role in cell division, according to new research at the University of California, San Francisco.

The Organized cell

(Phys.org)—An interdisciplinary effort at the Friedrich Miescher Institute for Biomedical Research (FMI) addressed the question of how mRNA content, which is translated into proteins, is regulated in the cell. Supported by the Swiss initiative for systems biology (SystemsX.ch), experimental biologists and computer scientists teamed up to contrast epigenomic data of histone modifications with post-transcriptional read-outs. Their study, published as a featured article in the journal Molecular Systems Biology, gives answer to a quantitative question in gene regulation.

Spread makes likely near-instantaneous DNA analysis

Picture this: You've brought your sick child to the doctor's office. After checking her pulse and blood pressure, he takes a nasal or throat swab and inserts it into a mysterious black box. Before the doctor finishes his examination, the black box beeps, indicating that the pathogen that's making your child sick has been identified.

Sound far-fetched? Actually, this scenario is closer to becoming a reality. Thanks to work by Reginald Beer and his team of scientists and engineers at DOE's Lawrence Livermore National Laboratory, sub-three-minute amplification of nucleic acids (DNA and RNA) via polymerase chain reaction (PCR) is now possible.

With three school-age children of his own, Beer knows all too well the frustration of waiting 24 to 48 hours for lab results to learn whether his sick youngster can be treated with antibiotics. "I was sitting in the pediatrician's office with my daughter several years ago, and it struck me that if we could make PCR fast and easy enough for use in doctors' offices, it would have a huge impact."

PCR is an indispensible technique in medical and biological research laboratories around the world. It allows researchers and clinicians to produce millions of copies from a single piece of DNA or RNA for use in genome sequencing, gene analysis, inheritable disease diagnosis, paternity testing, forensic identification, and the detection of infectious diseases.

Fresh technique helps researchers decode genomes

Although scientists sequenced the entire human genome more than 10 years ago, much work remains to understand what proteins all those genes code for.

Now, a study published online Aug. 27 in the Proceedings of the National Academy of Sciences describes a new approach that allows researchers to decode the genome by understanding where genes begin to encode for polypeptides, long chains of amino acids that make up proteins.

 "The key to decoding the genome knows exactly where the genes start to encode polypeptides," said Shu-Bing Qian, the paper's senior author and an assistant professor of nutritional sciences at Cornell. "If we know where they start, then we can predict what proteins they produce based on the gene's sequence.

Anchoring Proteins Effect Glucose Metabolism and Insulin Proclamation

(Sep. 4, 2012) — Scientists from the United States and Sweden have discovered a new control point that could be important as a drug target for the treatment of diabetes and other metabolic diseases. A-kinase anchoring proteins or AKAPs are known to influence the spatial distribution of kinases within the cell, crucial enzymes that control important molecular events related to the regulation of glucose levels in the blood.

In a new study published in The EMBO Journal, the team of researchers led by Simon Hinke and John Scott reveal for the first time that AKAPs influence the levels of glucose in the body by coordinating the spatial positioning of phosphatases, naturally occurring enzymes that counteract the effects of kinase enzymes.

New DNA-method

Tracks fish and whales in seawater

Sept. 4, 2012 — Danish researchers at the University of Copenhagen are using a new method for monitoring marine biodiversity and resources by using DNA traces in seawater to keep track of fish and whales. A half liter of seawater can contain evidence of local fish and whale faunas and eliminate the need for marine conservationists to employ traditional fishing methods in their work. The results of the new study have been published in PLOS ONE.

"The new DNA-method means that we can keep better track of life beneath the surface of the oceans around the world, and better monitor and protect ocean biodiversity and resources," says Ph.D. student Philip Francis Thomsen from the Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen.